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DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast
DNA polymerase epsilon (Pol ε) synthesizes the leading strands, following the CMG (Cdc45, Mcm2-7, and GINS [Go-Ichi-Nii-San]) helicase that translocates on the leading-strand template at eukaryotic replication forks. Although Pol ε is essential for the viability of fission and budding yeasts, the N-...
Autores principales: | Handa, Tetsuya, Kanke, Mai, Takahashi, Tatsuro S., Nakagawa, Takuro, Masukata, Hisao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418317/ https://www.ncbi.nlm.nih.gov/pubmed/22718908 http://dx.doi.org/10.1091/mbc.E12-05-0339 |
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