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Dopamine D(2) Antagonist-Induced Striatal Nur77 Expression Requires Activation of mGlu5 Receptors by Cortical Afferents

Dopamine D(2) receptor antagonists modulate gene transcription in the striatum. However, the molecular mechanism underlying this effect remains elusive. Here we used the expression of Nur77, a transcription factor of the orphan nuclear receptor family, as readout to explore the role of dopamine, glu...

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Detalles Bibliográficos
Autores principales:	Maheux, Jérôme, St-Hilaire, Michel, Voyer, David, Tirotta, Emanuele, Borrelli, Emiliana, Rouillard, Claude, Rompré, Pierre-Paul, Lévesque, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418524/ https://www.ncbi.nlm.nih.gov/pubmed/22912617 http://dx.doi.org/10.3389/fphar.2012.00153

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