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Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients

BACKGROUND: Sulfamethoxazole (SMX) is a commonly used antibiotic for prevention of infectious diseases associated with HIV/AIDS and immune-compromised states. SMX-induced hypersensitivity is an idiosyncratic cutaneous drug reaction with genetic components. Here, we tested association of candidate ge...

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Detalles Bibliográficos
Autores principales:	Wang, Danxin, Curtis, Amanda, Papp, Audrey C, Koletar, Susan L, Para, Michael F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418550/ https://www.ncbi.nlm.nih.gov/pubmed/22824134 http://dx.doi.org/10.1186/1755-8794-5-32

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