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Does the PI3K pathway promote or antagonize regulatory T cell development and function?

Regulatory T cells (Tregs) prevent autoimmunity and inflammation by suppressing the activation of other T cells and antigen presenting cells. The role of phosphoinositide 3-kinase (PI3K) signaling in Treg is controversial. Some studies suggest that inhibition of the PI3K pathway is essential for the...

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Detalles Bibliográficos
Autores principales:	Soond, Dalya R., Slack, Elizabeth C. M., Garden, Oliver A., Patton, Daniel T., Okkenhaug, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418637/ https://www.ncbi.nlm.nih.gov/pubmed/22912633 http://dx.doi.org/10.3389/fimmu.2012.00244

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