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Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline: APPLICATION TO PROTEIN ACETYLATION AND PHOSPHORYLATION
Despite advances in metabolic and postmetabolic labeling methods for quantitative proteomics, there remains a need for improved label-free approaches. This need is particularly pressing for workflows that incorporate affinity enrichment at the peptide level, where isobaric chemical labels such as is...
Autores principales: | Schilling, Birgit, Rardin, Matthew J., MacLean, Brendan X., Zawadzka, Anna M., Frewen, Barbara E., Cusack, Michael P., Sorensen, Dylan J., Bereman, Michael S., Jing, Enxuan, Wu, Christine C., Verdin, Eric, Kahn, C. Ronald, MacCoss, Michael J., Gibson, Bradford W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418851/ https://www.ncbi.nlm.nih.gov/pubmed/22454539 http://dx.doi.org/10.1074/mcp.M112.017707 |
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