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Transient early neurotrophin release and delayed inflammatory cytokine release by microglia in response to PAR-2 stimulation

Activated microglia exerts both beneficial and deleterious effects on neurons, but the signaling mechanism controlling these distinct responses remain unclear. We demonstrated that treatment of microglial cultures with the PAR-2 agonist, 2-Furoyl-LIGRLO-NH2, evoked early transient release of BDNF, w...

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Detalles Bibliográficos
Autores principales:	Chen, Chen-wen, Chen, Qian-bo, Ouyang, Qing, Sun, Ji-hu, Liu, Fang-ting, Song, Dian-wen, Yuan, Hong-bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419072/ https://www.ncbi.nlm.nih.gov/pubmed/22731117 http://dx.doi.org/10.1186/1742-2094-9-142

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