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Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

BACKGROUND: This study undertakes a systematic and comprehensive analysis of brain gene expression profiles of immune/inflammation-related genes in aging and Alzheimer’s disease (AD). METHODS: In a well-powered microarray study of young (20 to 59 years), aged (60 to 99 years), and AD (74 to 95 years...

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Detalles Bibliográficos
Autores principales:	Cribbs, David H, Berchtold, Nicole C, Perreau, Victoria, Coleman, Paul D, Rogers, Joseph, Tenner, Andrea J, Cotman, Carl W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419089/ https://www.ncbi.nlm.nih.gov/pubmed/22824372 http://dx.doi.org/10.1186/1742-2094-9-179

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