CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes

BACKGROUND: HIV latency is an obstacle for the eradication of HIV from infected individuals. Stable post-integration latency is controlled principally at the level of transcription. The HIV trans-activating protein, Tat, plays a key function in enhancing HIV transcriptional elongation. The HIV core...

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Detalles Bibliográficos
Autores principales: Wilhelm, Emmanuelle, Doyle, Marie-Christine, Nzaramba, Isaac, Magdzinski, Alexandre, Dumais, Nancy, Bell, Brendan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419132/
https://www.ncbi.nlm.nih.gov/pubmed/22834489
http://dx.doi.org/10.1186/1742-4690-9-62

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