RNA Inhibition Highlights Cyclin D1 as a Potential Therapeutic Target for Mantle Cell Lymphoma

Mantle cell lymphoma is characterized by a genetic translocation results in aberrant overexpression of the CCND1 gene, which encodes cyclin D1. This protein functions as a regulator of the cell cycle progression, hence is considered to play an important role in the pathogenesis of the disease. In th...

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Detalles Bibliográficos
Autores principales: Weinstein, Shiri, Emmanuel, Rafi, Jacobi, Ashley M., Abraham, Avigdor, Behlke, Mark A., Sprague, Andrew G., Novobrantseva, Tatiana I., Nagler, Arnon, Peer, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419170/
https://www.ncbi.nlm.nih.gov/pubmed/22905260
http://dx.doi.org/10.1371/journal.pone.0043343

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