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Induction of Multi-Functional T Cells in a Phase I Clinical Trial of Dendritic Cell Immunotherapy in Hepatitis C Virus Infected Individuals
We have previously reported a world-first phase I clinical trial to treat HCV patients using monocyte-derived dendritic cells (Mo-DC) loaded with HCV-specific lipopeptides. While the brief treatment proved to be safe, it failed to reduce the viral load and induced only transient cell-mediated immune...
Autores principales: | Li, Shuo, Roberts, Stuart, Plebanski, Magdalena, Gouillou, Maelenn, Spelman, Tim, Latour, Philippe, Jackson, David, Brown, Lorena, Sparrow, Rosemary L., Prince, H. Miles, Hart, Derek, Loveland, Bruce E., Gowans, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419178/ https://www.ncbi.nlm.nih.gov/pubmed/22905088 http://dx.doi.org/10.1371/journal.pone.0039368 |
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