Considerations in the Identification of Endogenous Substrates for Protein L-Isoaspartyl Methyltransferase: The Case of Synuclein

Protein L-isoaspartyl methyltransferase (PIMT) repairs abnormal isoaspartyl peptide bonds in age-damaged proteins. It has been reported that synuclein, a protein implicated in neurodegenerative diseases, is a major target of PIMT in mouse brain. To extend this finding and explore its possible releva...

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Detalles Bibliográficos
Autores principales: Morrison, Gareth J., Ganesan, Ranjani, Qin, Zhenxia, Aswad, Dana W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419188/
https://www.ncbi.nlm.nih.gov/pubmed/22905247
http://dx.doi.org/10.1371/journal.pone.0043288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419188/
https://www.ncbi.nlm.nih.gov/pubmed/22905247
http://dx.doi.org/10.1371/journal.pone.0043288

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