Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation

BACKGROUND: The transient receptor potential ankyrin 1 (TRPA1) channel, localized to airway sensory nerves, has been proposed to mediate airway inflammation evoked by allergen and cigarette smoke (CS) in rodents, via a neurogenic mechanism. However the limited clinical evidence for the role of neuro...

Descripción completa

Detalles Bibliográficos
Autores principales: Nassini, Romina, Pedretti, Pamela, Moretto, Nadia, Fusi, Camilla, Carnini, Chiara, Facchinetti, Fabrizio, Viscomi, Arturo Roberto, Pisano, Anna Rita, Stokesberry, Susan, Brunmark, Charlott, Svitacheva, Naila, McGarvey, Lorcan, Patacchini, Riccardo, Damholt, Anders B., Geppetti, Pierangelo, Materazzi, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419223/
https://www.ncbi.nlm.nih.gov/pubmed/22905134
http://dx.doi.org/10.1371/journal.pone.0042454

Ejemplares similares

Ejemplares similares