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Relationships between PrP(Sc) Stability and Incubation Time for United States Scrapie Isolates in a Natural Host System

Transmissible spongiform encephalopathies (TSEs), including scrapie in sheep (Ovis aries), are fatal neurodegenerative diseases caused by the misfolding of the cellular prion protein (PrP(C)) into a â-rich conformer (PrP(Sc)) that accumulates into higher-order structures in the brain and other tissu...

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Detalles Bibliográficos
Autores principales:	Vrentas, Catherine E., Greenlee, Justin J., Tatum, Trudy L., Nicholson, Eric M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419241/ https://www.ncbi.nlm.nih.gov/pubmed/22916207 http://dx.doi.org/10.1371/journal.pone.0043060

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