Dendritic cell expression of A20 preserves immune homeostasis and prevents colitis and spondyloarthritis

Dendritic cells (DCs), known to support immune activation during infections, may also regulate immune homeostasis in resting animals. Here we show that mice lacking A20 specifically in DCs spontaneously exhibited DC activation and expansion of activated T cells. DC-specific epistasis experiments usi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hammer, Gianna Elena, Turer, Emre E., Taylor, Kimberly E., Fang, Celia J., Advincula, Rommel, Oshima, Shigeru, Barrera, Julio, Huang, Eric J., Hou, Baidong, Malynn, Barbara A., Reizis, Boris, DeFranco, Anthony, Criswell, Lindsey A., Nakamura, Mary C., Ma, Averil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419270/
https://www.ncbi.nlm.nih.gov/pubmed/22019834
http://dx.doi.org/10.1038/ni.2135

Ejemplares similares

Ejemplares similares