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Optimal flux spaces of genome-scale stoichiometric models are determined by a few subnetworks
The metabolism of organisms can be studied with comprehensive stoichiometric models of their metabolic networks. Flux balance analysis (FBA) calculates optimal metabolic performance of stoichiometric models. However, detailed biological interpretation of FBA is limited because, in general, a huge nu...
Autores principales: | Kelk, Steven M., Olivier, Brett G., Stougie, Leen, Bruggeman, Frank J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419370/ https://www.ncbi.nlm.nih.gov/pubmed/22896812 http://dx.doi.org/10.1038/srep00580 |
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