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Optimal flux spaces of genome-scale stoichiometric models are determined by a few subnetworks

The metabolism of organisms can be studied with comprehensive stoichiometric models of their metabolic networks. Flux balance analysis (FBA) calculates optimal metabolic performance of stoichiometric models. However, detailed biological interpretation of FBA is limited because, in general, a huge nu...

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Detalles Bibliográficos
Autores principales: Kelk, Steven M., Olivier, Brett G., Stougie, Leen, Bruggeman, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419370/
https://www.ncbi.nlm.nih.gov/pubmed/22896812
http://dx.doi.org/10.1038/srep00580

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