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Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas
Aberrant wnt pathway activation through cytoplasmic stabilization of β-catenin is crucial for the development of various human malignancies. In gliomagenesis, the role of canonical (i.e., β-catenin-dependent) signalling is largely unknown. Here, we studied canonical wnt pathway activation in 15 shor...
Autores principales: | Schüle, Rebecca, Dictus, Christine, Campos, Benito, Wan, Feng, Felsberg, Jörg, Ahmadi, Rezvan, Centner, Franz-Simon, Grabe, Niels, Reifenberger, Guido, Bermejo, Justo L., Unterberg, Andreas, Herold-Mende, Christel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific World Journal
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419426/ https://www.ncbi.nlm.nih.gov/pubmed/22919349 http://dx.doi.org/10.1100/2012/697313 |
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