Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation

BACKGROUND: The mechanisms of progressive dopaminergic neuronal loss in Parkinson’s disease (PD) remain poorly understood, largely due to the complex etiology and multifactorial nature of disease pathogenesis. Several lines of evidence from human studies and experimental models over the last decade...

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Detalles Bibliográficos
Autores principales: Gordon, Richard, Anantharam, Vellareddy, Kanthasamy, Anumantha G, Kanthasamy, Arthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419619/
https://www.ncbi.nlm.nih.gov/pubmed/22540228
http://dx.doi.org/10.1186/1742-2094-9-82

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