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Imbalance of placental regulatory T cell and Th17 cell population dynamics in the FIV-infected pregnant cat

BACKGROUND: An appropriate balance in placental regulatory T cells (Tregs), an immunosuppressive cell population, and Th17 cells, a pro-inflammatory cell population, is essential in allowing tolerance of the semi-allogeneic fetus. TGF-β and IL-6 are cytokines that promote differentiation of Tregs an...

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Detalles Bibliográficos
Autores principales: Boudreaux, Crystal E, Chumbley, Lyndon B, Scott, Veronica L, Wise, Dwayne A, Coats, Karen S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419658/
https://www.ncbi.nlm.nih.gov/pubmed/22559012
http://dx.doi.org/10.1186/1743-422X-9-88

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