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Characterization and Functional Analysis of the Calmodulin-Binding Domain of Rac1 GTPase

Rac1, a member of the Rho family of small GTPases, has been shown to promote formation of lamellipodia at the leading edge of motile cells and affect cell migration. We previously demonstrated that calmodulin can bind to a region in the C-terminal of Rac1 and that this interaction is important in th...

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Detalles Bibliográficos
Autores principales: Xu, Bing, Chelikani, Prashen, Bhullar, Rajinder P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419704/
https://www.ncbi.nlm.nih.gov/pubmed/22905193
http://dx.doi.org/10.1371/journal.pone.0042975

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