C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut Granules

The human disease Hermansky-Pudlak syndrome results from defective biogenesis of lysosome-related organelles (LROs) and can be caused by mutations in subunits of the BLOC-1 complex. Here we show that C. elegans glo-2 and snpn-1, despite relatively low levels of amino acid identity, encode Pallidin a...

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Detalles Bibliográficos
Autores principales: Hermann, Greg J., Scavarda, Emily, Weis, Allison M., Saxton, Daniel S., Thomas, Laura L., Salesky, Rebecca, Somhegyi, Hannah, Curtin, Thomas P., Barrett, Alec, Foster, Olivia K., Vine, Annalise, Erlich, Katherine, Kwan, Elizabeth, Rabbitts, Beverley M., Warren, Kaila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419718/
https://www.ncbi.nlm.nih.gov/pubmed/22916203
http://dx.doi.org/10.1371/journal.pone.0043043

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