Efficacy of a Novel Class of RNA Interference Therapeutic Agents

RNA interference (RNAi) is being widely used in functional gene research and is an important tool for drug discovery. However, canonical double-stranded short interfering RNAs are unstable and induce undesirable adverse effects, and thus there is no currently RNAi-based therapy in the clinic. We hav...

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Detalles Bibliográficos
Autores principales: Hamasaki, Tomohiro, Suzuki, Hiroshi, Shirohzu, Hisao, Matsumoto, Takahiro, D'Alessandro-Gabazza, Corina N., Gil-Bernabe, Paloma, Boveda-Ruiz, Daniel, Naito, Masahiro, Kobayashi, Tetsu, Toda, Masaaki, Mizutani, Takayuki, Taguchi, Osamu, Morser, John, Eguchi, Yutaka, Kuroda, Masahiko, Ochiya, Takahiro, Hayashi, Hirotake, Gabazza, Esteban C., Ohgi, Tadaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419724/
https://www.ncbi.nlm.nih.gov/pubmed/22916145
http://dx.doi.org/10.1371/journal.pone.0042655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419724/
https://www.ncbi.nlm.nih.gov/pubmed/22916145
http://dx.doi.org/10.1371/journal.pone.0042655

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