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Akt1 mediates prostate cancer cell microinvasion and chemotaxis to metastatic stimuli via integrin β(3) affinity modulation

BACKGROUND: Activation of Akt and increased expression of integrin β(3) are the two most important changes that have been linked to the attainment of metastatic potential by prostate cancer cells. However, a direct link between Akt activity and inside-out activation of integrin β(3) in mediating pro...

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Detalles Bibliográficos
Autores principales:	Goc, A, Liu, J, Byzova, T V, Somanath, P R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419951/ https://www.ncbi.nlm.nih.gov/pubmed/22767145 http://dx.doi.org/10.1038/bjc.2012.295

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