Role of mineralocorticoid receptor/Rho/Rho-kinase pathway in obesity-related renal injury

OBJECTIVE: We examined whether aldosterone/Rho/Rho-kinase pathway contributed to obesity-associated nephropathy. SUBJECTS: C57BL/6J mice were fed a high fat or low fat diet, and mice on a high fat diet were treated with a mineralocorticoid receptor antagonist, eplerenone. RESULTS: The mice on a high...

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Detalles Bibliográficos
Autores principales: Tokuyama, H, Wakino, S, Hara, Y, Washida, N, Fujimura, K, Hosoya, K, Yoshioka, K, Hasegawa, K, Minakuchi, H, Homma, K, Hayashi, K, Itoh, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419977/
https://www.ncbi.nlm.nih.gov/pubmed/22184057
http://dx.doi.org/10.1038/ijo.2011.232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419977/
https://www.ncbi.nlm.nih.gov/pubmed/22184057
http://dx.doi.org/10.1038/ijo.2011.232

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