Cargando…

Role of mineralocorticoid receptor/Rho/Rho-kinase pathway in obesity-related renal injury

OBJECTIVE: We examined whether aldosterone/Rho/Rho-kinase pathway contributed to obesity-associated nephropathy. SUBJECTS: C57BL/6J mice were fed a high fat or low fat diet, and mice on a high fat diet were treated with a mineralocorticoid receptor antagonist, eplerenone. RESULTS: The mice on a high...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tokuyama, H, Wakino, S, Hara, Y, Washida, N, Fujimura, K, Hosoya, K, Yoshioka, K, Hasegawa, K, Minakuchi, H, Homma, K, Hayashi, K, Itoh, H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419977/ https://www.ncbi.nlm.nih.gov/pubmed/22184057 http://dx.doi.org/10.1038/ijo.2011.232

Ejemplares similares

Ghrelin Protects against Renal Damages Induced by Angiotensin-II via an Antioxidative Stress Mechanism in Mice
por: Fujimura, Keiko, et al.
Publicado: (2014)

The Functional Significance of the Rho/Rho-Kinase Pathway in Human Erythrocytes
por: Tiftik, R. Nalan, et al.
Publicado: (2014)

RhoA/Rho kinase in spinal cord injury
por: Wu, Xiangbing, et al.
Publicado: (2016)

TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway
por: Thoppil, Roslin J., et al.
Publicado: (2016)

Ephrin-A5 Induces Collapse of Growth Cones by Activating Rho and Rho Kinase
por: Wahl, Siegfried, et al.
Publicado: (2000)

Vascular dysfunction in obese diabetic db/db mice involves the interplay between aldosterone/mineralocorticoid receptor and Rho kinase signaling
por: Nguyen Dinh Cat, Aurelie, et al.
Publicado: (2018)

ROCK (RhoA/Rho Kinase) in Cardiovascular–Renal Pathophysiology: A Review of New Advancements
por: Seccia, Teresa M., et al.
Publicado: (2020)

Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntington’s Disease
por: Narayanan, K. Lakshmi, et al.
Publicado: (2015)

An emerging treatment option for glaucoma: Rho kinase inhibitors
por: Wang, Sean K, et al.
Publicado: (2014)

High Basolateral Glucose Increases Sodium-Glucose Cotransporter 2 and Reduces Sirtuin-1 in Renal Tubules through Glucose Transporter-2 Detection
por: Umino, Hiroyuki, et al.
Publicado: (2018)

The role of RhoA/Rho kinase pathway in endothelial dysfunction
por: Yao, Lin, et al.
Publicado: (2010)

Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells
por: Ramachandran, C., et al.
Publicado: (2011)

Insight Into Rho Kinase Isoforms in Obesity and Energy Homeostasis
por: Wei, Lei, et al.
Publicado: (2022)

Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism
por: Singh, Rajesh K., et al.
Publicado: (2017)

Peptide Substrates for Rho-Associated Kinase 2 (Rho-Kinase 2/ROCK2)
por: Kang, Jeong-Hun, et al.
Publicado: (2011)

RhoA/Rho‐kinases in asthma: from pathogenesis to therapeutic targets
por: Zhang, Yan, et al.
Publicado: (2020)

RhoA improves cryopreservation of rooster sperm through the Rho/RhoA-associated kinase/cofilin pathway
por: Heng, Nuo, et al.
Publicado: (2022)

Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules
por: Futatsugi, Koji, et al.
Publicado: (2016)

Measurement of exclusive $\rho^{+}\rho^{-}$ production in mid-virtuality two-photon interactions and study of the $\gamma \gamma^{*} \to \rho\rho$ process at LEP
por: Achard, P., et al.
Publicado: (2005)

Rho Kinase in Eye Disease
por: Okumura, Naoki, et al.
Publicado: (2017)

The effect of aldosterone and aldosterone blockade on the progression of chronic kidney disease: a randomized placebo-controlled clinical trial
por: Minakuchi, Hitoshi, et al.
Publicado: (2020)

RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension
por: Barman, Scott A, et al.
Publicado: (2009)

RhoA/Rho-Kinase and Nitric Oxide in Vascular Reactivity in Rats with Endotoxaemia
por: Liao, Mei-Hui, et al.
Publicado: (2013)

Tramadol regulates the activation of human platelets via Rac but not Rho/Rho-kinase
por: Iida, Hiroki, et al.
Publicado: (2023)

Oral adsorbent AST-120 ameliorates gut environment and protects against the progression of renal impairment in CKD rats
por: Yoshifuji, Ayumi, et al.
Publicado: (2018)

The GTP binding proteins Gem and Rad are negative regulators of the Rho–Rho kinase pathway
por: Ward, Yvona, et al.
Publicado: (2002)

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia
por: Yan, Ya-yun, et al.
Publicado: (2015)

Inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide
por: Nalli, Ancy D., et al.
Publicado: (2017)

$B \to \rho \pi, B \to \rho \rho$ and the measurement of $\alpha$ at LHCb
por: Robbe, Patrick
Publicado: (2006)

Protein Kinase A Governs a RhoA-RhoGDI Protrusion-Retraction Pacemaker in Migrating Cells
por: Tkachenko, Eugene, et al.
Publicado: (2011)

The activation of ezrin–radixin–moesin proteins is regulated by netrin-1 through Src kinase and RhoA/Rho kinase activities and mediates netrin-1–induced axon outgrowth
por: Antoine-Bertrand, Judith, et al.
Publicado: (2011)

Supersymmetric contribution to the electroweak rho parameter
por: Drees, Manuel, et al.
Publicado: (1990)

A Case Report of Autosomal Dominant Polycystic Kidney Disease Under Peritoneal Dialysis With Cyst Infection and Culture-Positive Peritoneal Fluid
por: Yasuda, Itaru, et al.
Publicado: (2019)

Investigation of rho+, rho- and rho0 production in pi+p interactions at 16 GeV/c and pp interactions at 24 GeV/c and quark model predictions
por: Böckmann, Klaus, et al.
Publicado: (1978)

Implications of the RhoA/Rho associated kinase pathway and leptin in primary uterine inertia in the dog
por: FREHNER, Bianca Lourdes, et al.
Publicado: (2021)

RhoA phosphorylation mediated by Rho/RhoA-associated kinase pathway improves the anti-freezing potentiality of murine hatched and diapaused blastocysts
por: Gu, Meichao, et al.
Publicado: (2017)

Direct Rho-associated kinase inhibiton induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells
por: Zhang, Zhiqun, et al.
Publicado: (2006)

ROS-dependent activation of RhoA/Rho-kinase in pulmonary artery: Role of Src-family kinases and ARHGEF1
por: MacKay, Charles E., et al.
Publicado: (2017)

Vascular Stiffening Mediated by Rho‐Associated Coiled‐Coil Containing Kinase Isoforms
por: Li, Yuxin, et al.
Publicado: (2021)

Inhibition of RhoA/Rho kinase signaling pathway by fasudil protects against kainic acid‐induced neurite injury
por: Xiang, Yingchun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4nbullsqna0gfb3eju35q30t18