A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression

By analyzing public data sets of gene expression in human breast cancers we observed that increased levels of transcripts encoding the planar cell polarity (PCP) proteins SCRIB and VANGL1 correlate with increased risk of patient relapse. Experimentally, we found that reducing expression of SCRIB by...

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Detalles Bibliográficos
Autores principales: Anastas, J N, Biechele, T L, Robitaille, M, Muster, J, Allison, K H, Angers, S, Moon, R T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419983/
https://www.ncbi.nlm.nih.gov/pubmed/22179838
http://dx.doi.org/10.1038/onc.2011.528

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