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Induction of Mitochondrial Changes Associated with Oxidative Stress on Very Long Chain Fatty Acids (C22:0, C24:0, or C26:0)-Treated Human Neuronal Cells (SK-NB-E)

In Alzheimer's disease, lipid alterations point towards peroxisomal dysfunctions. Indeed, a cortical accumulation of saturated very long chain fatty acids (VLCFAs: C22:0, C24:0, C26:0), substrates for peroxisomal β-oxidation, has been found in Alzheimer patients. This study was realized to inve...

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Detalles Bibliográficos
Autores principales: Zarrouk, Amira, Vejux, Anne, Nury, Thomas, El Hajj, Hammam I., Haddad, Madouda, Cherkaoui-Malki, Mustapha, Riedinger, Jean-Marc, Hammami, Mohamed, Lizard, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420217/
https://www.ncbi.nlm.nih.gov/pubmed/22919440
http://dx.doi.org/10.1155/2012/623257