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Thymus-autonomous T cell development in the absence of progenitor import

Thymus function is thought to depend on a steady supply of T cell progenitors from the bone marrow. The notion that the thymus lacks progenitors with self-renewal capacity is based on thymus transplantation experiments in which host-derived thymocytes replaced thymus-resident cells within 4 wk. Thym...

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Detalles Bibliográficos
Autores principales:	Martins, Vera C., Ruggiero, Eliana, Schlenner, Susan M., Madan, Vikas, Schmidt, Manfred, Fink, Pamela J., von Kalle, Christof, Rodewald, Hans-Reimer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420332/ https://www.ncbi.nlm.nih.gov/pubmed/22778389 http://dx.doi.org/10.1084/jem.20120846

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