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Schizophrenia as a Disorder of Social Communication

Evidence is reviewed for the existence of a core system for moment-to-moment social communication that is based on the perception of dynamic gestures and other social perceptual processes in the temporal-parietal occipital junction (TPJ), including the posterior superior temporal sulcus (PSTS) and s...

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Autor principal: Wible, Cynthia Gayle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420370/
https://www.ncbi.nlm.nih.gov/pubmed/22966453
http://dx.doi.org/10.1155/2012/920485
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author Wible, Cynthia Gayle
author_facet Wible, Cynthia Gayle
author_sort Wible, Cynthia Gayle
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description Evidence is reviewed for the existence of a core system for moment-to-moment social communication that is based on the perception of dynamic gestures and other social perceptual processes in the temporal-parietal occipital junction (TPJ), including the posterior superior temporal sulcus (PSTS) and surrounding regions. Overactivation of these regions may produce the schizophrenic syndrome. The TPJ plays a key role in the perception and production of dynamic social, emotional, and attentional gestures for the self and others. These include dynamic gestures of the body, face, and eyes as well as audiovisual speech and prosody. Many negative symptoms are characterized by deficits in responding within these domains. Several properties of this system have been discovered through single neuron recording, brain stimulation, neuroimaging, and the study of neurological impairment. These properties map onto the schizophrenic syndrome. The representation of dynamic gestures is multimodal (auditory, visual, and tactile), matching the predominant hallucinatory categories in schizophrenia. Inherent in the perceptual signal of gesture representation is a computation of intention, agency, and anticipation or expectancy (for the self and others). The neurons are also tuned or biased to rapidly detect threat-related emotions. I review preliminary evidence that overactivation of this system can result in schizophrenia.
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spelling pubmed-34203702012-09-10 Schizophrenia as a Disorder of Social Communication Wible, Cynthia Gayle Schizophr Res Treatment Review Article Evidence is reviewed for the existence of a core system for moment-to-moment social communication that is based on the perception of dynamic gestures and other social perceptual processes in the temporal-parietal occipital junction (TPJ), including the posterior superior temporal sulcus (PSTS) and surrounding regions. Overactivation of these regions may produce the schizophrenic syndrome. The TPJ plays a key role in the perception and production of dynamic social, emotional, and attentional gestures for the self and others. These include dynamic gestures of the body, face, and eyes as well as audiovisual speech and prosody. Many negative symptoms are characterized by deficits in responding within these domains. Several properties of this system have been discovered through single neuron recording, brain stimulation, neuroimaging, and the study of neurological impairment. These properties map onto the schizophrenic syndrome. The representation of dynamic gestures is multimodal (auditory, visual, and tactile), matching the predominant hallucinatory categories in schizophrenia. Inherent in the perceptual signal of gesture representation is a computation of intention, agency, and anticipation or expectancy (for the self and others). The neurons are also tuned or biased to rapidly detect threat-related emotions. I review preliminary evidence that overactivation of this system can result in schizophrenia. Hindawi Publishing Corporation 2012 2012-05-20 /pmc/articles/PMC3420370/ /pubmed/22966453 http://dx.doi.org/10.1155/2012/920485 Text en Copyright © 2012 Cynthia Gayle Wible. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Wible, Cynthia Gayle
Schizophrenia as a Disorder of Social Communication
title Schizophrenia as a Disorder of Social Communication
title_full Schizophrenia as a Disorder of Social Communication
title_fullStr Schizophrenia as a Disorder of Social Communication
title_full_unstemmed Schizophrenia as a Disorder of Social Communication
title_short Schizophrenia as a Disorder of Social Communication
title_sort schizophrenia as a disorder of social communication
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420370/
https://www.ncbi.nlm.nih.gov/pubmed/22966453
http://dx.doi.org/10.1155/2012/920485
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