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Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus

Background. Scleredema adultorum, a connective tissue disorder of unknown aetiology, is characterized by a thickening of the reticular dermis in the upper back of the body that may decrease the mobility of the affected tissues. It has been reported in diabetic patients with poor metabolic control. T...

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Autores principales: Martín, C., Requena, L., Manrique, K., Manzarbeitia, F. D., Rovira, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420415/
https://www.ncbi.nlm.nih.gov/pubmed/22937286
http://dx.doi.org/10.1155/2011/560273
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author Martín, C.
Requena, L.
Manrique, K.
Manzarbeitia, F. D.
Rovira, A.
author_facet Martín, C.
Requena, L.
Manrique, K.
Manzarbeitia, F. D.
Rovira, A.
author_sort Martín, C.
collection PubMed
description Background. Scleredema adultorum, a connective tissue disorder of unknown aetiology, is characterized by a thickening of the reticular dermis in the upper back of the body that may decrease the mobility of the affected tissues. It has been reported in diabetic patients with poor metabolic control. Therapeutic options are limited with generally poor results. Case Report. 53-year-old white male with type 2 diabetes mellitus was referred to our department for evaluation of incipient nephropathy and retinopathy. On examination, he presented erythematous, indurated, painless and ill-defined plaque on the skin of the upper back with limited movement of shoulders. A biopsy was done revealing scleredema. PUVA treatment and physiotherapy were started with the amelioration of mobility and acquiring some elasticity of the upper back. Discussion. The development of scleredema in diabetic patients has been related to prolonged exposure to chronic hyperglycaemia. Our patient has had diabetes for 20 years with an acceptable glucose control, however he developed the scleredema 10 years ago. Conclusions. Scleredema is a rare connective disorder that seems to appear most frequently in diabetic subjects. Good metabolic control seems not to preclude its development. PUVA treatment and physiotherapy are therapeutic options that seem to be of some help.
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spelling pubmed-34204152012-08-30 Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus Martín, C. Requena, L. Manrique, K. Manzarbeitia, F. D. Rovira, A. Case Rep Endocrinol Case Report Background. Scleredema adultorum, a connective tissue disorder of unknown aetiology, is characterized by a thickening of the reticular dermis in the upper back of the body that may decrease the mobility of the affected tissues. It has been reported in diabetic patients with poor metabolic control. Therapeutic options are limited with generally poor results. Case Report. 53-year-old white male with type 2 diabetes mellitus was referred to our department for evaluation of incipient nephropathy and retinopathy. On examination, he presented erythematous, indurated, painless and ill-defined plaque on the skin of the upper back with limited movement of shoulders. A biopsy was done revealing scleredema. PUVA treatment and physiotherapy were started with the amelioration of mobility and acquiring some elasticity of the upper back. Discussion. The development of scleredema in diabetic patients has been related to prolonged exposure to chronic hyperglycaemia. Our patient has had diabetes for 20 years with an acceptable glucose control, however he developed the scleredema 10 years ago. Conclusions. Scleredema is a rare connective disorder that seems to appear most frequently in diabetic subjects. Good metabolic control seems not to preclude its development. PUVA treatment and physiotherapy are therapeutic options that seem to be of some help. Hindawi Publishing Corporation 2011 2011-07-31 /pmc/articles/PMC3420415/ /pubmed/22937286 http://dx.doi.org/10.1155/2011/560273 Text en Copyright © 2011 C. Martín et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Martín, C.
Requena, L.
Manrique, K.
Manzarbeitia, F. D.
Rovira, A.
Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus
title Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus
title_full Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus
title_fullStr Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus
title_full_unstemmed Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus
title_short Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus
title_sort scleredema diabeticorum in a patient with type 2 diabetes mellitus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420415/
https://www.ncbi.nlm.nih.gov/pubmed/22937286
http://dx.doi.org/10.1155/2011/560273
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