Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery

Immune reconstitution inflammatory syndrome (IRIS) in the setting of antiretroviral therapy is well described, but it is not as common in non-HIV patients; here, we present a case of immune reconstitution inflammatory syndrome presenting as acute respiratory distress syndrome in a leukemia patient w...

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Autores principales: Alawin, Issam A., Karnath, Bernard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420500/
https://www.ncbi.nlm.nih.gov/pubmed/22928127
http://dx.doi.org/10.1155/2012/670347
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author Alawin, Issam A.
Karnath, Bernard M.
author_facet Alawin, Issam A.
Karnath, Bernard M.
author_sort Alawin, Issam A.
collection PubMed
description Immune reconstitution inflammatory syndrome (IRIS) in the setting of antiretroviral therapy is well described, but it is not as common in non-HIV patients; here, we present a case of immune reconstitution inflammatory syndrome presenting as acute respiratory distress syndrome in a leukemia patient who had neutropenic fever and septic shock after high-dose cytarabine. During neutropenia recovery, his chest X-ray showed progressive worsening despite being on adequate therapy, we started him on steroids which resulted in significant clinical improvement.
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spelling pubmed-34205002012-08-27 Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery Alawin, Issam A. Karnath, Bernard M. Case Rep Hematol Case Report Immune reconstitution inflammatory syndrome (IRIS) in the setting of antiretroviral therapy is well described, but it is not as common in non-HIV patients; here, we present a case of immune reconstitution inflammatory syndrome presenting as acute respiratory distress syndrome in a leukemia patient who had neutropenic fever and septic shock after high-dose cytarabine. During neutropenia recovery, his chest X-ray showed progressive worsening despite being on adequate therapy, we started him on steroids which resulted in significant clinical improvement. Hindawi Publishing Corporation 2012 2012-06-11 /pmc/articles/PMC3420500/ /pubmed/22928127 http://dx.doi.org/10.1155/2012/670347 Text en Copyright © 2012 I. A. Alawin and B. M. Karnath. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Alawin, Issam A.
Karnath, Bernard M.
Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery
title Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery
title_full Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery
title_fullStr Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery
title_full_unstemmed Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery
title_short Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery
title_sort paradoxical immune reconstitution syndrome presenting as acute respiratory distress syndrome in a leukemia patient during neutrophil recovery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420500/
https://www.ncbi.nlm.nih.gov/pubmed/22928127
http://dx.doi.org/10.1155/2012/670347
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