The Coexistence of Systemic Lupus Erythematosus and Thyrotoxicosis: The Diagnostic Value of Antihistone Antibodies

We report four female patients with Graves' disease with positive ANA antibodies and possibility for development of systemic lupus erythematosus. All four patients have been treated with antithyroid drugs. SLE symptoms have appeared from 4 to 12 months after the beginning of therapy with methys...

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Autores principales: Baleva, Marta, Nikolov, Krasimir, Manov, Emil, Stoikov, Anastas, Shabani, Rebhat, Dourmishev, Lyubomir, Nikolova, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420510/
https://www.ncbi.nlm.nih.gov/pubmed/22937453
http://dx.doi.org/10.1155/2012/517059
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author Baleva, Marta
Nikolov, Krasimir
Manov, Emil
Stoikov, Anastas
Shabani, Rebhat
Dourmishev, Lyubomir
Nikolova, Milena
author_facet Baleva, Marta
Nikolov, Krasimir
Manov, Emil
Stoikov, Anastas
Shabani, Rebhat
Dourmishev, Lyubomir
Nikolova, Milena
author_sort Baleva, Marta
collection PubMed
description We report four female patients with Graves' disease with positive ANA antibodies and possibility for development of systemic lupus erythematosus. All four patients have been treated with antithyroid drugs. SLE symptoms have appeared from 4 to 12 months after the beginning of therapy with methysol in two of them. The third patient had no symptoms for SLE, but her ANA, anti-DNA, and antihistone antibodies had been positive at the time of the onset of thyrotoxicosis. The fourth patient had alopecia areata with positive ANA and antihistone antibodies.
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spelling pubmed-34205102012-08-30 The Coexistence of Systemic Lupus Erythematosus and Thyrotoxicosis: The Diagnostic Value of Antihistone Antibodies Baleva, Marta Nikolov, Krasimir Manov, Emil Stoikov, Anastas Shabani, Rebhat Dourmishev, Lyubomir Nikolova, Milena Case Rep Rheumatol Case Report We report four female patients with Graves' disease with positive ANA antibodies and possibility for development of systemic lupus erythematosus. All four patients have been treated with antithyroid drugs. SLE symptoms have appeared from 4 to 12 months after the beginning of therapy with methysol in two of them. The third patient had no symptoms for SLE, but her ANA, anti-DNA, and antihistone antibodies had been positive at the time of the onset of thyrotoxicosis. The fourth patient had alopecia areata with positive ANA and antihistone antibodies. Hindawi Publishing Corporation 2012 2012-04-09 /pmc/articles/PMC3420510/ /pubmed/22937453 http://dx.doi.org/10.1155/2012/517059 Text en Copyright © 2012 Marta Baleva et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Baleva, Marta
Nikolov, Krasimir
Manov, Emil
Stoikov, Anastas
Shabani, Rebhat
Dourmishev, Lyubomir
Nikolova, Milena
The Coexistence of Systemic Lupus Erythematosus and Thyrotoxicosis: The Diagnostic Value of Antihistone Antibodies
title The Coexistence of Systemic Lupus Erythematosus and Thyrotoxicosis: The Diagnostic Value of Antihistone Antibodies
title_full The Coexistence of Systemic Lupus Erythematosus and Thyrotoxicosis: The Diagnostic Value of Antihistone Antibodies
title_fullStr The Coexistence of Systemic Lupus Erythematosus and Thyrotoxicosis: The Diagnostic Value of Antihistone Antibodies
title_full_unstemmed The Coexistence of Systemic Lupus Erythematosus and Thyrotoxicosis: The Diagnostic Value of Antihistone Antibodies
title_short The Coexistence of Systemic Lupus Erythematosus and Thyrotoxicosis: The Diagnostic Value of Antihistone Antibodies
title_sort coexistence of systemic lupus erythematosus and thyrotoxicosis: the diagnostic value of antihistone antibodies
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420510/
https://www.ncbi.nlm.nih.gov/pubmed/22937453
http://dx.doi.org/10.1155/2012/517059
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