Rituximab-Induced Coronary Vasospasm

Rituximab has improved the treatment of B-cell non-Hodgkin lymphomas. While it is generally well tolerated, serious adverse effects including infusion reactions with hemodynamic compromise and cardiac arrhythmias or ischemia are possible. We report a case of coronary vasospasm occurring during a rit...

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Detalles Bibliográficos
Autores principales: Lee, Linda, Kukreti, Vishal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420582/
https://www.ncbi.nlm.nih.gov/pubmed/22953082
http://dx.doi.org/10.1155/2012/984986
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author Lee, Linda
Kukreti, Vishal
author_facet Lee, Linda
Kukreti, Vishal
author_sort Lee, Linda
collection PubMed
description Rituximab has improved the treatment of B-cell non-Hodgkin lymphomas. While it is generally well tolerated, serious adverse effects including infusion reactions with hemodynamic compromise and cardiac arrhythmias or ischemia are possible. We report a case of coronary vasospasm occurring during a rituximab infusion in a patient with minimal tumour burden and who had no cardiac risk factors. This case highlights that determination of the cause of ischemia is important and may identify some patients who can be successfully rechallenged.
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spelling pubmed-34205822012-09-05 Rituximab-Induced Coronary Vasospasm Lee, Linda Kukreti, Vishal Case Rep Hematol Case Report Rituximab has improved the treatment of B-cell non-Hodgkin lymphomas. While it is generally well tolerated, serious adverse effects including infusion reactions with hemodynamic compromise and cardiac arrhythmias or ischemia are possible. We report a case of coronary vasospasm occurring during a rituximab infusion in a patient with minimal tumour burden and who had no cardiac risk factors. This case highlights that determination of the cause of ischemia is important and may identify some patients who can be successfully rechallenged. Hindawi Publishing Corporation 2012 2012-06-06 /pmc/articles/PMC3420582/ /pubmed/22953082 http://dx.doi.org/10.1155/2012/984986 Text en Copyright © 2012 L. Lee and V. Kukreti. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Linda
Kukreti, Vishal
Rituximab-Induced Coronary Vasospasm
title Rituximab-Induced Coronary Vasospasm
title_full Rituximab-Induced Coronary Vasospasm
title_fullStr Rituximab-Induced Coronary Vasospasm
title_full_unstemmed Rituximab-Induced Coronary Vasospasm
title_short Rituximab-Induced Coronary Vasospasm
title_sort rituximab-induced coronary vasospasm
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420582/
https://www.ncbi.nlm.nih.gov/pubmed/22953082
http://dx.doi.org/10.1155/2012/984986
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