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Familial Bell's Palsy: A Case Report and Literature Review

Objective. To describe a unique case of familial Bell's palsy and summarize the current literature regarding possible hereditary influences. Design. Case report. Main Outcome Measures. Clinical exam, CSF analysis, and family history provided per the patient. Results. We report the case of a 58-...

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Detalles Bibliográficos
Autores principales: Kubik, Mark, Robles, Liliana, Kung, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420608/
https://www.ncbi.nlm.nih.gov/pubmed/22934210
http://dx.doi.org/10.1155/2012/674981
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author Kubik, Mark
Robles, Liliana
Kung, Doris
author_facet Kubik, Mark
Robles, Liliana
Kung, Doris
author_sort Kubik, Mark
collection PubMed
description Objective. To describe a unique case of familial Bell's palsy and summarize the current literature regarding possible hereditary influences. Design. Case report. Main Outcome Measures. Clinical exam, CSF analysis, and family history provided per the patient. Results. We report the case of a 58-year-old female who presented with recurrent and bilateral episodes of facial palsy. The patient underwent multiple CSF investigations to rule out a possible infectious and rheumatologic etiology that were all negative. Further questioning revealed she was one of seven family members with a history of unilateral facial nerve paralysis. Conclusion. The sheer number of similar case studies to date suggests that familial clustering of Bell's palsy is a real, noncoincidental phenomenon. Our case represents a unique and perplexing example of one such family. Familial Bell's palsy may represent an autoimmune disease secondary to inherited HLA alloantigens or a structural predisposition to disease based on the dimensions of the facial canal.
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spelling pubmed-34206082012-08-29 Familial Bell's Palsy: A Case Report and Literature Review Kubik, Mark Robles, Liliana Kung, Doris Case Rep Neurol Med Case Report Objective. To describe a unique case of familial Bell's palsy and summarize the current literature regarding possible hereditary influences. Design. Case report. Main Outcome Measures. Clinical exam, CSF analysis, and family history provided per the patient. Results. We report the case of a 58-year-old female who presented with recurrent and bilateral episodes of facial palsy. The patient underwent multiple CSF investigations to rule out a possible infectious and rheumatologic etiology that were all negative. Further questioning revealed she was one of seven family members with a history of unilateral facial nerve paralysis. Conclusion. The sheer number of similar case studies to date suggests that familial clustering of Bell's palsy is a real, noncoincidental phenomenon. Our case represents a unique and perplexing example of one such family. Familial Bell's palsy may represent an autoimmune disease secondary to inherited HLA alloantigens or a structural predisposition to disease based on the dimensions of the facial canal. Hindawi Publishing Corporation 2012 2012-08-05 /pmc/articles/PMC3420608/ /pubmed/22934210 http://dx.doi.org/10.1155/2012/674981 Text en Copyright © 2012 Mark Kubik et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kubik, Mark
Robles, Liliana
Kung, Doris
Familial Bell's Palsy: A Case Report and Literature Review
title Familial Bell's Palsy: A Case Report and Literature Review
title_full Familial Bell's Palsy: A Case Report and Literature Review
title_fullStr Familial Bell's Palsy: A Case Report and Literature Review
title_full_unstemmed Familial Bell's Palsy: A Case Report and Literature Review
title_short Familial Bell's Palsy: A Case Report and Literature Review
title_sort familial bell's palsy: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420608/
https://www.ncbi.nlm.nih.gov/pubmed/22934210
http://dx.doi.org/10.1155/2012/674981
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