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Familial Bell's Palsy: A Case Report and Literature Review
Objective. To describe a unique case of familial Bell's palsy and summarize the current literature regarding possible hereditary influences. Design. Case report. Main Outcome Measures. Clinical exam, CSF analysis, and family history provided per the patient. Results. We report the case of a 58-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420608/ https://www.ncbi.nlm.nih.gov/pubmed/22934210 http://dx.doi.org/10.1155/2012/674981 |
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author | Kubik, Mark Robles, Liliana Kung, Doris |
author_facet | Kubik, Mark Robles, Liliana Kung, Doris |
author_sort | Kubik, Mark |
collection | PubMed |
description | Objective. To describe a unique case of familial Bell's palsy and summarize the current literature regarding possible hereditary influences. Design. Case report. Main Outcome Measures. Clinical exam, CSF analysis, and family history provided per the patient. Results. We report the case of a 58-year-old female who presented with recurrent and bilateral episodes of facial palsy. The patient underwent multiple CSF investigations to rule out a possible infectious and rheumatologic etiology that were all negative. Further questioning revealed she was one of seven family members with a history of unilateral facial nerve paralysis. Conclusion. The sheer number of similar case studies to date suggests that familial clustering of Bell's palsy is a real, noncoincidental phenomenon. Our case represents a unique and perplexing example of one such family. Familial Bell's palsy may represent an autoimmune disease secondary to inherited HLA alloantigens or a structural predisposition to disease based on the dimensions of the facial canal. |
format | Online Article Text |
id | pubmed-3420608 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-34206082012-08-29 Familial Bell's Palsy: A Case Report and Literature Review Kubik, Mark Robles, Liliana Kung, Doris Case Rep Neurol Med Case Report Objective. To describe a unique case of familial Bell's palsy and summarize the current literature regarding possible hereditary influences. Design. Case report. Main Outcome Measures. Clinical exam, CSF analysis, and family history provided per the patient. Results. We report the case of a 58-year-old female who presented with recurrent and bilateral episodes of facial palsy. The patient underwent multiple CSF investigations to rule out a possible infectious and rheumatologic etiology that were all negative. Further questioning revealed she was one of seven family members with a history of unilateral facial nerve paralysis. Conclusion. The sheer number of similar case studies to date suggests that familial clustering of Bell's palsy is a real, noncoincidental phenomenon. Our case represents a unique and perplexing example of one such family. Familial Bell's palsy may represent an autoimmune disease secondary to inherited HLA alloantigens or a structural predisposition to disease based on the dimensions of the facial canal. Hindawi Publishing Corporation 2012 2012-08-05 /pmc/articles/PMC3420608/ /pubmed/22934210 http://dx.doi.org/10.1155/2012/674981 Text en Copyright © 2012 Mark Kubik et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kubik, Mark Robles, Liliana Kung, Doris Familial Bell's Palsy: A Case Report and Literature Review |
title | Familial Bell's Palsy: A Case Report and Literature Review |
title_full | Familial Bell's Palsy: A Case Report and Literature Review |
title_fullStr | Familial Bell's Palsy: A Case Report and Literature Review |
title_full_unstemmed | Familial Bell's Palsy: A Case Report and Literature Review |
title_short | Familial Bell's Palsy: A Case Report and Literature Review |
title_sort | familial bell's palsy: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420608/ https://www.ncbi.nlm.nih.gov/pubmed/22934210 http://dx.doi.org/10.1155/2012/674981 |
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