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Challenges in Management of Primary Hypoparathyroidism Associated with Autoimmune Polyglandular Syndrome Type 1

We report a case of autoimmune polyglandular syndrome type 1 (APS1) complicated by severe vascular insufficiency due to diffuse vascular calcification. APS1 is characterised clinically by multiple autoimmune conditions and development of at least two components of the triad of mucocutaneous candidia...

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Detalles Bibliográficos
Autores principales: Wallace, I. R., McConnell, V., Bell, P. M., Lindsay, J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420681/
https://www.ncbi.nlm.nih.gov/pubmed/22937280
http://dx.doi.org/10.1155/2011/281758
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author Wallace, I. R.
McConnell, V.
Bell, P. M.
Lindsay, J. R.
author_facet Wallace, I. R.
McConnell, V.
Bell, P. M.
Lindsay, J. R.
author_sort Wallace, I. R.
collection PubMed
description We report a case of autoimmune polyglandular syndrome type 1 (APS1) complicated by severe vascular insufficiency due to diffuse vascular calcification. APS1 is characterised clinically by multiple autoimmune conditions and development of at least two components of the triad of mucocutaneous candidiasis, hypoparathyroidism, and autoimmune adrenal insufficiency. We highlight the problems in current serum calcium monitoring methods and suggest that fluctuations in serum calcium concentrations due to difficulties treating hypoparathyroidism may have contributed to the vascular calcification seen in this case.
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spelling pubmed-34206812012-08-30 Challenges in Management of Primary Hypoparathyroidism Associated with Autoimmune Polyglandular Syndrome Type 1 Wallace, I. R. McConnell, V. Bell, P. M. Lindsay, J. R. Case Rep Endocrinol Case Report We report a case of autoimmune polyglandular syndrome type 1 (APS1) complicated by severe vascular insufficiency due to diffuse vascular calcification. APS1 is characterised clinically by multiple autoimmune conditions and development of at least two components of the triad of mucocutaneous candidiasis, hypoparathyroidism, and autoimmune adrenal insufficiency. We highlight the problems in current serum calcium monitoring methods and suggest that fluctuations in serum calcium concentrations due to difficulties treating hypoparathyroidism may have contributed to the vascular calcification seen in this case. Hindawi Publishing Corporation 2011 2011-09-07 /pmc/articles/PMC3420681/ /pubmed/22937280 http://dx.doi.org/10.1155/2011/281758 Text en Copyright © 2011 I. R. Wallace et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wallace, I. R.
McConnell, V.
Bell, P. M.
Lindsay, J. R.
Challenges in Management of Primary Hypoparathyroidism Associated with Autoimmune Polyglandular Syndrome Type 1
title Challenges in Management of Primary Hypoparathyroidism Associated with Autoimmune Polyglandular Syndrome Type 1
title_full Challenges in Management of Primary Hypoparathyroidism Associated with Autoimmune Polyglandular Syndrome Type 1
title_fullStr Challenges in Management of Primary Hypoparathyroidism Associated with Autoimmune Polyglandular Syndrome Type 1
title_full_unstemmed Challenges in Management of Primary Hypoparathyroidism Associated with Autoimmune Polyglandular Syndrome Type 1
title_short Challenges in Management of Primary Hypoparathyroidism Associated with Autoimmune Polyglandular Syndrome Type 1
title_sort challenges in management of primary hypoparathyroidism associated with autoimmune polyglandular syndrome type 1
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420681/
https://www.ncbi.nlm.nih.gov/pubmed/22937280
http://dx.doi.org/10.1155/2011/281758
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