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Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report

Introduction. Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. Case Presentation. Because of increasing epigastric and...

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Autores principales: Hardt, Aline, Stippel, Dirk, Odenthal, Margarete, Hölscher, Arnulf H., Dienes, Hans-Peter, Drebber, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420693/
https://www.ncbi.nlm.nih.gov/pubmed/22934212
http://dx.doi.org/10.1155/2012/195607
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author Hardt, Aline
Stippel, Dirk
Odenthal, Margarete
Hölscher, Arnulf H.
Dienes, Hans-Peter
Drebber, Uta
author_facet Hardt, Aline
Stippel, Dirk
Odenthal, Margarete
Hölscher, Arnulf H.
Dienes, Hans-Peter
Drebber, Uta
author_sort Hardt, Aline
collection PubMed
description Introduction. Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. Case Presentation. Because of increasing epigastric and abdominal pain, abdominal ultrasound was performed in a 37-year-old male professional bodybuilder. A hyperechoic lesion in the liver was detected in segment VI. The magnetic resonance imaging showed hepatomegaly and confirmed the lesion, which showed features of a hepatocellular adenoma (HCA). Laboratory values were inconspicuous. After laparoscopic segmentectomy the histological examination revealed HCC. Conclusion. While the development of HCA in the liver by chronic intake of AAS is well known, little is known about the association with HCC. The presented case may indicate aetiological association of chronic intake of AAS and the development of HCC.
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spelling pubmed-34206932012-08-29 Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report Hardt, Aline Stippel, Dirk Odenthal, Margarete Hölscher, Arnulf H. Dienes, Hans-Peter Drebber, Uta Case Rep Pathol Case Report Introduction. Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. Case Presentation. Because of increasing epigastric and abdominal pain, abdominal ultrasound was performed in a 37-year-old male professional bodybuilder. A hyperechoic lesion in the liver was detected in segment VI. The magnetic resonance imaging showed hepatomegaly and confirmed the lesion, which showed features of a hepatocellular adenoma (HCA). Laboratory values were inconspicuous. After laparoscopic segmentectomy the histological examination revealed HCC. Conclusion. While the development of HCA in the liver by chronic intake of AAS is well known, little is known about the association with HCC. The presented case may indicate aetiological association of chronic intake of AAS and the development of HCC. Hindawi Publishing Corporation 2012 2012-07-05 /pmc/articles/PMC3420693/ /pubmed/22934212 http://dx.doi.org/10.1155/2012/195607 Text en Copyright © 2012 Aline Hardt et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hardt, Aline
Stippel, Dirk
Odenthal, Margarete
Hölscher, Arnulf H.
Dienes, Hans-Peter
Drebber, Uta
Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_full Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_fullStr Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_full_unstemmed Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_short Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_sort development of hepatocellular carcinoma associated with anabolic androgenic steroid abuse in a young bodybuilder: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420693/
https://www.ncbi.nlm.nih.gov/pubmed/22934212
http://dx.doi.org/10.1155/2012/195607
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