Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature

We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopen...

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Detalles Bibliográficos
Autores principales: Gilbertson, Michael, Tuckfield, Annabel, Juneja, Surender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420701/
https://www.ncbi.nlm.nih.gov/pubmed/22937318
http://dx.doi.org/10.1155/2012/167653
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author Gilbertson, Michael
Tuckfield, Annabel
Juneja, Surender
author_facet Gilbertson, Michael
Tuckfield, Annabel
Juneja, Surender
author_sort Gilbertson, Michael
collection PubMed
description We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion.
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spelling pubmed-34207012012-08-30 Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature Gilbertson, Michael Tuckfield, Annabel Juneja, Surender Case Rep Hematol Case Report We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion. Hindawi Publishing Corporation 2012 2012-04-12 /pmc/articles/PMC3420701/ /pubmed/22937318 http://dx.doi.org/10.1155/2012/167653 Text en Copyright © 2012 Michael Gilbertson et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gilbertson, Michael
Tuckfield, Annabel
Juneja, Surender
Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_full Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_fullStr Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_full_unstemmed Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_short Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_sort myelodysplastic syndrome with t(1;7) associated with marked dysmegakarypoiesis & severe thrombocytopenia: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420701/
https://www.ncbi.nlm.nih.gov/pubmed/22937318
http://dx.doi.org/10.1155/2012/167653
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AT tuckfieldannabel myelodysplasticsyndromewitht17associatedwithmarkeddysmegakarypoiesisseverethrombocytopeniaacasereportandreviewoftheliterature
AT junejasurender myelodysplasticsyndromewitht17associatedwithmarkeddysmegakarypoiesisseverethrombocytopeniaacasereportandreviewoftheliterature

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