First Report of a Case of Pneumococcal Meningitis Which Did Not Respond to the Ceftriaxone Therapy despite the Isolated Organism Being Sensitive to This Antibiotic In Vitro

A 60-year-old man presented with pneumococcal meningitis which did not respond to the ceftriaxone therapy, in spite of in-vitro susceptibility (minimal inhibitory concentration of 0.016 μg/dLit) of the isolated organism to this antibacterial agent, although ceftriaxone is still the drug of choice fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Mojtabavi, Maryam, Naderi, Hamid Reza, Tavanaee Sani, Ashraf, Bagheri, Mahmood, Ghazvini, Kiarash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420714/
https://www.ncbi.nlm.nih.gov/pubmed/22937426
http://dx.doi.org/10.1155/2011/485952
_version_ 1782240906997399552
author Mojtabavi, Maryam
Naderi, Hamid Reza
Tavanaee Sani, Ashraf
Bagheri, Mahmood
Ghazvini, Kiarash
author_facet Mojtabavi, Maryam
Naderi, Hamid Reza
Tavanaee Sani, Ashraf
Bagheri, Mahmood
Ghazvini, Kiarash
author_sort Mojtabavi, Maryam
collection PubMed
description A 60-year-old man presented with pneumococcal meningitis which did not respond to the ceftriaxone therapy, in spite of in-vitro susceptibility (minimal inhibitory concentration of 0.016 μg/dLit) of the isolated organism to this antibacterial agent, although ceftriaxone is still the drug of choice for such pneumococcal meningitis. Review of published articles revealed no report of clinical resistance in organisms which were susceptible to the same antimicrobial agent in vitro. This alarming emergence of isolates with in vivo resistance should be considered and even could lead to a shift in the empirical antibiotic therapy for pneumococcal infections.
format Online
Article
Text
id pubmed-3420714
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-34207142012-08-30 First Report of a Case of Pneumococcal Meningitis Which Did Not Respond to the Ceftriaxone Therapy despite the Isolated Organism Being Sensitive to This Antibiotic In Vitro Mojtabavi, Maryam Naderi, Hamid Reza Tavanaee Sani, Ashraf Bagheri, Mahmood Ghazvini, Kiarash Case Rep Pulmonol Case Report A 60-year-old man presented with pneumococcal meningitis which did not respond to the ceftriaxone therapy, in spite of in-vitro susceptibility (minimal inhibitory concentration of 0.016 μg/dLit) of the isolated organism to this antibacterial agent, although ceftriaxone is still the drug of choice for such pneumococcal meningitis. Review of published articles revealed no report of clinical resistance in organisms which were susceptible to the same antimicrobial agent in vitro. This alarming emergence of isolates with in vivo resistance should be considered and even could lead to a shift in the empirical antibiotic therapy for pneumococcal infections. Hindawi Publishing Corporation 2011 2011-10-25 /pmc/articles/PMC3420714/ /pubmed/22937426 http://dx.doi.org/10.1155/2011/485952 Text en Copyright © 2011 Maryam Mojtabavi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mojtabavi, Maryam
Naderi, Hamid Reza
Tavanaee Sani, Ashraf
Bagheri, Mahmood
Ghazvini, Kiarash
First Report of a Case of Pneumococcal Meningitis Which Did Not Respond to the Ceftriaxone Therapy despite the Isolated Organism Being Sensitive to This Antibiotic In Vitro
title First Report of a Case of Pneumococcal Meningitis Which Did Not Respond to the Ceftriaxone Therapy despite the Isolated Organism Being Sensitive to This Antibiotic In Vitro
title_full First Report of a Case of Pneumococcal Meningitis Which Did Not Respond to the Ceftriaxone Therapy despite the Isolated Organism Being Sensitive to This Antibiotic In Vitro
title_fullStr First Report of a Case of Pneumococcal Meningitis Which Did Not Respond to the Ceftriaxone Therapy despite the Isolated Organism Being Sensitive to This Antibiotic In Vitro
title_full_unstemmed First Report of a Case of Pneumococcal Meningitis Which Did Not Respond to the Ceftriaxone Therapy despite the Isolated Organism Being Sensitive to This Antibiotic In Vitro
title_short First Report of a Case of Pneumococcal Meningitis Which Did Not Respond to the Ceftriaxone Therapy despite the Isolated Organism Being Sensitive to This Antibiotic In Vitro
title_sort first report of a case of pneumococcal meningitis which did not respond to the ceftriaxone therapy despite the isolated organism being sensitive to this antibiotic in vitro
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420714/
https://www.ncbi.nlm.nih.gov/pubmed/22937426
http://dx.doi.org/10.1155/2011/485952
work_keys_str_mv AT mojtabavimaryam firstreportofacaseofpneumococcalmeningitiswhichdidnotrespondtotheceftriaxonetherapydespitetheisolatedorganismbeingsensitivetothisantibioticinvitro
AT naderihamidreza firstreportofacaseofpneumococcalmeningitiswhichdidnotrespondtotheceftriaxonetherapydespitetheisolatedorganismbeingsensitivetothisantibioticinvitro
AT tavanaeesaniashraf firstreportofacaseofpneumococcalmeningitiswhichdidnotrespondtotheceftriaxonetherapydespitetheisolatedorganismbeingsensitivetothisantibioticinvitro
AT bagherimahmood firstreportofacaseofpneumococcalmeningitiswhichdidnotrespondtotheceftriaxonetherapydespitetheisolatedorganismbeingsensitivetothisantibioticinvitro
AT ghazvinikiarash firstreportofacaseofpneumococcalmeningitiswhichdidnotrespondtotheceftriaxonetherapydespitetheisolatedorganismbeingsensitivetothisantibioticinvitro

Ejemplares similares