Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case

The thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems,...

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Autores principales: Regragui, S., Amelal, S., Astati, S., Zine, M., Alami Drideb, N., Al Bouzidi, A., Messaoudi, N., Benkirane, M., Doghmi, K., Mikdame, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420723/
https://www.ncbi.nlm.nih.gov/pubmed/22953078
http://dx.doi.org/10.1155/2012/806476
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author Regragui, S.
Amelal, S.
Astati, S.
Zine, M.
Alami Drideb, N.
Al Bouzidi, A.
Messaoudi, N.
Benkirane, M.
Doghmi, K.
Mikdame, M.
author_facet Regragui, S.
Amelal, S.
Astati, S.
Zine, M.
Alami Drideb, N.
Al Bouzidi, A.
Messaoudi, N.
Benkirane, M.
Doghmi, K.
Mikdame, M.
author_sort Regragui, S.
collection PubMed
description The thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems, organ transplants, and cancer. Other forms are secondary to drugs including antimitotics. We report the case of a patient followed for acute myelogenous leukemia. She received induction chemotherapy combining daunorubicin and cytarabine, complicated by thrombotic thrombocytopenic purpura.
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spelling pubmed-34207232012-09-05 Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case Regragui, S. Amelal, S. Astati, S. Zine, M. Alami Drideb, N. Al Bouzidi, A. Messaoudi, N. Benkirane, M. Doghmi, K. Mikdame, M. Case Rep Hematol Case Report The thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems, organ transplants, and cancer. Other forms are secondary to drugs including antimitotics. We report the case of a patient followed for acute myelogenous leukemia. She received induction chemotherapy combining daunorubicin and cytarabine, complicated by thrombotic thrombocytopenic purpura. Hindawi Publishing Corporation 2012 2012-05-07 /pmc/articles/PMC3420723/ /pubmed/22953078 http://dx.doi.org/10.1155/2012/806476 Text en Copyright © 2012 S. Regragui et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Regragui, S.
Amelal, S.
Astati, S.
Zine, M.
Alami Drideb, N.
Al Bouzidi, A.
Messaoudi, N.
Benkirane, M.
Doghmi, K.
Mikdame, M.
Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case
title Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case
title_full Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case
title_fullStr Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case
title_full_unstemmed Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case
title_short Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case
title_sort thrombotic microangiopathy with skin localization secondary to cytarabine-daunorubicin association: report of a case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420723/
https://www.ncbi.nlm.nih.gov/pubmed/22953078
http://dx.doi.org/10.1155/2012/806476
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