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Posaconazole-Vincristine Coadministration Triggers Seizure in a Young Female Adult: A Case Report

Coadministration of azoles and vincristine has been shown to increase vincristine neurotoxic effects due to the inhibition of cytochrome P450 (CYP) isoform 3A4, for which vincristine is a substrate. Despite the absence of any casual relationship between seizure and coadministration of azoles, few ca...

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Detalles Bibliográficos
Autores principales: Hamdy, Dalia A., El-Geed, Hager, El-Salem, Samah, Zaidan, Manal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420769/
https://www.ncbi.nlm.nih.gov/pubmed/22937325
http://dx.doi.org/10.1155/2012/343742