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Posaconazole-Vincristine Coadministration Triggers Seizure in a Young Female Adult: A Case Report
Coadministration of azoles and vincristine has been shown to increase vincristine neurotoxic effects due to the inhibition of cytochrome P450 (CYP) isoform 3A4, for which vincristine is a substrate. Despite the absence of any casual relationship between seizure and coadministration of azoles, few ca...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420769/ https://www.ncbi.nlm.nih.gov/pubmed/22937325 http://dx.doi.org/10.1155/2012/343742 |