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Similar hematological and biochemical parameters among periodontitis and control group subjects

OBJECTIVE: There are conflicting reports in the past literature documenting the tendency of anemia in patients with periodontitis. Hence, this study was undertaken to assess whether periodontitis may cause an anemic state, by evaluating and comparing the red blood cell count, levels of hemoglobin, h...

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Autores principales: Prakash, Shobha, Dhingra, Kunaal, Priya, Shanmuga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dental Investigations Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420836/
https://www.ncbi.nlm.nih.gov/pubmed/22904657
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author Prakash, Shobha
Dhingra, Kunaal
Priya, Shanmuga
author_facet Prakash, Shobha
Dhingra, Kunaal
Priya, Shanmuga
author_sort Prakash, Shobha
collection PubMed
description OBJECTIVE: There are conflicting reports in the past literature documenting the tendency of anemia in patients with periodontitis. Hence, this study was undertaken to assess whether periodontitis may cause an anemic state, by evaluating and comparing the red blood cell count, levels of hemoglobin, hematocrit, erythrocyte sedimentation rate (ESR), serum iron and serum ferritin between subjects with and without periodontitis. METHODS: In this cross-sectional study, 140 systemically healthy subjects of both sexes (mean age 46 years) were recruited as control group (50 subjects without periodontitis) and study groups comprising 30 patients each with mild, moderate and severe chronic generalized periodontitis. Periodontal parameters and orthopantamographs were taken for all the groups and then 5 mL venous blood samples were sent for complete blood count and biochemical analysis. Inter-group and intra-group comparisons were performed for all the assessed parameters. RESULTS: The periodontal parameters were significantly higher (P⩽.05) in periodontitis patients. Except for the ESR, which was significantly higher (P=.03) in the mild periodontitis group than the control group, hematological and biochemical parameters were not significantly different (P>.05) among the study groups or between the control and study groups. This difference was not evident even among the male and female subjects of both control and study groups (P>.05). CONCLUSIONS: Within the limits of this cross-sectional study, it can be concluded that the presence and severity of periodontitis may not affect the hematological and biochemical parameters of an individual. Further long term studies are however encouraged to validate these findings.
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spelling pubmed-34208362012-08-17 Similar hematological and biochemical parameters among periodontitis and control group subjects Prakash, Shobha Dhingra, Kunaal Priya, Shanmuga Eur J Dent Articles OBJECTIVE: There are conflicting reports in the past literature documenting the tendency of anemia in patients with periodontitis. Hence, this study was undertaken to assess whether periodontitis may cause an anemic state, by evaluating and comparing the red blood cell count, levels of hemoglobin, hematocrit, erythrocyte sedimentation rate (ESR), serum iron and serum ferritin between subjects with and without periodontitis. METHODS: In this cross-sectional study, 140 systemically healthy subjects of both sexes (mean age 46 years) were recruited as control group (50 subjects without periodontitis) and study groups comprising 30 patients each with mild, moderate and severe chronic generalized periodontitis. Periodontal parameters and orthopantamographs were taken for all the groups and then 5 mL venous blood samples were sent for complete blood count and biochemical analysis. Inter-group and intra-group comparisons were performed for all the assessed parameters. RESULTS: The periodontal parameters were significantly higher (P⩽.05) in periodontitis patients. Except for the ESR, which was significantly higher (P=.03) in the mild periodontitis group than the control group, hematological and biochemical parameters were not significantly different (P>.05) among the study groups or between the control and study groups. This difference was not evident even among the male and female subjects of both control and study groups (P>.05). CONCLUSIONS: Within the limits of this cross-sectional study, it can be concluded that the presence and severity of periodontitis may not affect the hematological and biochemical parameters of an individual. Further long term studies are however encouraged to validate these findings. Dental Investigations Society 2012-07 /pmc/articles/PMC3420836/ /pubmed/22904657 Text en Copyright 2012 European Journal of Dentistry. All rights reserved.
spellingShingle Articles
Prakash, Shobha
Dhingra, Kunaal
Priya, Shanmuga
Similar hematological and biochemical parameters among periodontitis and control group subjects
title Similar hematological and biochemical parameters among periodontitis and control group subjects
title_full Similar hematological and biochemical parameters among periodontitis and control group subjects
title_fullStr Similar hematological and biochemical parameters among periodontitis and control group subjects
title_full_unstemmed Similar hematological and biochemical parameters among periodontitis and control group subjects
title_short Similar hematological and biochemical parameters among periodontitis and control group subjects
title_sort similar hematological and biochemical parameters among periodontitis and control group subjects
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420836/
https://www.ncbi.nlm.nih.gov/pubmed/22904657
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