Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis

Association testing of multiple correlated phenotypes offers better power than univariate analysis of single traits. We analyzed 6,600 individuals from two population-based cohorts with both genome-wide SNP data and serum metabolomic profiles. From the observed correlation structure of 130 metabolit...

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Detalles Bibliográficos
Autores principales: Inouye, Michael, Ripatti, Samuli, Kettunen, Johannes, Lyytikäinen, Leo-Pekka, Oksala, Niku, Laurila, Pirkka-Pekka, Kangas, Antti J., Soininen, Pasi, Savolainen, Markku J., Viikari, Jorma, Kähönen, Mika, Perola, Markus, Salomaa, Veikko, Raitakari, Olli, Lehtimäki, Terho, Taskinen, Marja-Riitta, Järvelin, Marjo-Riitta, Ala-Korpela, Mika, Palotie, Aarno, de Bakker, Paul I. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420921/
https://www.ncbi.nlm.nih.gov/pubmed/22916037
http://dx.doi.org/10.1371/journal.pgen.1002907

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