CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction

Chronic viral infections lead to persistent CD8 T cell activation and functional exhaustion. Expression of programmed cell death-1 (PD-1) has been associated to CD8 T cell dysfunction in HIV infection. Herein we report that another negative regulator of T cell activation, CD160, was also upregulated...

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Detalles Bibliográficos
Autores principales: Peretz, Yoav, He, Zhong, Shi, Yu, Yassine-Diab, Bader, Goulet, Jean-Philippe, Bordi, Rebeka, Filali-Mouhim, Ali, Loubert, Jean-Baptiste, El-Far, Mohamed, Dupuy, Franck P., Boulassel, Mohamed Rachid, Tremblay, Cécile, Routy, Jean-Pierre, Bernard, Nicole, Balderas, Robert, Haddad, Elias K., Sékaly, Rafick-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420930/
https://www.ncbi.nlm.nih.gov/pubmed/22916009
http://dx.doi.org/10.1371/journal.ppat.1002840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420930/
https://www.ncbi.nlm.nih.gov/pubmed/22916009
http://dx.doi.org/10.1371/journal.ppat.1002840

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