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S Phase–Coupled E2f1 Destruction Ensures Homeostasis in Proliferating Tissues
Precise control of cell cycle regulators is critical for normal development and tissue homeostasis. E2F transcription factors are activated during G1 to drive the G1-S transition and are then inhibited during S phase by a variety of mechanisms. Here, we genetically manipulate the single Drosophila a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420931/ https://www.ncbi.nlm.nih.gov/pubmed/22916021 http://dx.doi.org/10.1371/journal.pgen.1002831 |