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Self-Enhancement of Hepatitis C Virus Replication by Promotion of Specific Sphingolipid Biosynthesis

Lipids are key components in the viral life cycle that affect host-pathogen interactions. In this study, we investigated the effect of HCV infection on sphingolipid metabolism, especially on endogenous SM levels, and the relationship between HCV replication and endogenous SM molecular species. We de...

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Detalles Bibliográficos
Autores principales: Hirata, Yuichi, Ikeda, Kazutaka, Sudoh, Masayuki, Tokunaga, Yuko, Suzuki, Akemi, Weng, Leiyun, Ohta, Masatoshi, Tobita, Yoshimi, Okano, Ken, Ozeki, Kazuhisa, Kawasaki, Kenichi, Tsukuda, Takuo, Katsume, Asao, Aoki, Yuko, Umehara, Takuya, Sekiguchi, Satoshi, Toyoda, Tetsuya, Shimotohno, Kunitada, Soga, Tomoyoshi, Nishijima, Masahiro, Taguchi, Ryo, Kohara, Michinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420934/
https://www.ncbi.nlm.nih.gov/pubmed/22916015
http://dx.doi.org/10.1371/journal.ppat.1002860