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Self-Enhancement of Hepatitis C Virus Replication by Promotion of Specific Sphingolipid Biosynthesis
Lipids are key components in the viral life cycle that affect host-pathogen interactions. In this study, we investigated the effect of HCV infection on sphingolipid metabolism, especially on endogenous SM levels, and the relationship between HCV replication and endogenous SM molecular species. We de...
Autores principales: | Hirata, Yuichi, Ikeda, Kazutaka, Sudoh, Masayuki, Tokunaga, Yuko, Suzuki, Akemi, Weng, Leiyun, Ohta, Masatoshi, Tobita, Yoshimi, Okano, Ken, Ozeki, Kazuhisa, Kawasaki, Kenichi, Tsukuda, Takuo, Katsume, Asao, Aoki, Yuko, Umehara, Takuya, Sekiguchi, Satoshi, Toyoda, Tetsuya, Shimotohno, Kunitada, Soga, Tomoyoshi, Nishijima, Masahiro, Taguchi, Ryo, Kohara, Michinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420934/ https://www.ncbi.nlm.nih.gov/pubmed/22916015 http://dx.doi.org/10.1371/journal.ppat.1002860 |
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