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Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome

The zebrafish is a powerful experimental system for uncovering gene function in vertebrate organisms. Nevertheless, studies in the zebrafish have been limited by the approaches available for eliminating gene function. Here we present simple and efficient methods for inducing, detecting, and recoveri...

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Detalles Bibliográficos
Autores principales:	Dahlem, Timothy J., Hoshijima, Kazuyuki, Jurynec, Michael J., Gunther, Derrick, Starker, Colby G., Locke, Alexandra S., Weis, Allison M., Voytas, Daniel F., Grunwald, David Jonah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420959/ https://www.ncbi.nlm.nih.gov/pubmed/22916025 http://dx.doi.org/10.1371/journal.pgen.1002861

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