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The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells

Dynamic interactions between intracellular networks regulate cellular homeostasis and responses to perturbations. Targeted therapy is aimed at perturbing oncogene addiction pathways in cancer, however, development of acquired resistance to these drugs is a significant clinical problem. A network-bas...

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Detalles Bibliográficos
Autores principales:	Komurov, Kakajan, Tseng, Jen-Te, Muller, Melissa, Seviour, Elena G, Moss, Tyler J, Yang, Lifeng, Nagrath, Deepak, Ram, Prahlad T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Molecular Biology Organization 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421441/ https://www.ncbi.nlm.nih.gov/pubmed/22864381 http://dx.doi.org/10.1038/msb.2012.25

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