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Effect of Iron Containing Supplements on Rats’ Dental Caries Progression

OBJECTIVE: Iron deficiency is the most common form of malnutrition in developing countries. Iron containing supplements have been used effectively to solve this problem. In children, because of teeth staining after taking iron drops, parents have the idea that iron drops are the cause of tooth decay...

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Autores principales: Eshghi, AR., Kowsari-Isfahan, R., Rezaiefar, M., Razavi, M., Zeighami, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422058/
https://www.ncbi.nlm.nih.gov/pubmed/22924097
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author Eshghi, AR.
Kowsari-Isfahan, R.
Rezaiefar, M.
Razavi, M.
Zeighami, S.
author_facet Eshghi, AR.
Kowsari-Isfahan, R.
Rezaiefar, M.
Razavi, M.
Zeighami, S.
author_sort Eshghi, AR.
collection PubMed
description OBJECTIVE: Iron deficiency is the most common form of malnutrition in developing countries. Iron containing supplements have been used effectively to solve this problem. In children, because of teeth staining after taking iron drops, parents have the idea that iron drops are the cause of tooth decay; therefore, they limit this vital supplement in their children’s diet. Hereby, we evaluate the histologic effect of iron containing supplements on tooth caries in rice rats with cariogenic or non-cariogenic diet. MATERIALS AND METHODS: Twelve rats were selected and divided into four groups for this interventional experimental study. Four different types of dietary regimens were used for four months; group A, cariogenic diet with iron containing supplements; group B, cariogenic diet without iron containing supplements; group C, non-cariogenic diet with iron containing supplements; group D, non-cariogenic diet without iron containing supplements. After sacrificing the rats, 20-micron histological sections of their posterior teeth were prepared using the Ground Section method, then they were studied under polarized light microscopy. In order to compare the progression of caries in different samples, the depth of the lesions in the enamel was measured as three grades I, II and III. RESULTS: The mean grade value of A, B, C and D groups were 1.61, 2.61, 1.37 and 1.80, respectively. Statistical analysis revealed that significantly fewer caries were seen in the group which had received iron containing supplements and cariogenic diet compared with cariogenic diet without iron supplements (p<0.05). CONCLUSION: Ferrous sulfate reduces the progression of dental caries in the cariogenic dietary regimen.
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spelling pubmed-34220582012-08-24 Effect of Iron Containing Supplements on Rats’ Dental Caries Progression Eshghi, AR. Kowsari-Isfahan, R. Rezaiefar, M. Razavi, M. Zeighami, S. J Dent (Tehran) Original Article OBJECTIVE: Iron deficiency is the most common form of malnutrition in developing countries. Iron containing supplements have been used effectively to solve this problem. In children, because of teeth staining after taking iron drops, parents have the idea that iron drops are the cause of tooth decay; therefore, they limit this vital supplement in their children’s diet. Hereby, we evaluate the histologic effect of iron containing supplements on tooth caries in rice rats with cariogenic or non-cariogenic diet. MATERIALS AND METHODS: Twelve rats were selected and divided into four groups for this interventional experimental study. Four different types of dietary regimens were used for four months; group A, cariogenic diet with iron containing supplements; group B, cariogenic diet without iron containing supplements; group C, non-cariogenic diet with iron containing supplements; group D, non-cariogenic diet without iron containing supplements. After sacrificing the rats, 20-micron histological sections of their posterior teeth were prepared using the Ground Section method, then they were studied under polarized light microscopy. In order to compare the progression of caries in different samples, the depth of the lesions in the enamel was measured as three grades I, II and III. RESULTS: The mean grade value of A, B, C and D groups were 1.61, 2.61, 1.37 and 1.80, respectively. Statistical analysis revealed that significantly fewer caries were seen in the group which had received iron containing supplements and cariogenic diet compared with cariogenic diet without iron supplements (p<0.05). CONCLUSION: Ferrous sulfate reduces the progression of dental caries in the cariogenic dietary regimen. Tehran University of Medical Sciences 2012 2012-03-31 /pmc/articles/PMC3422058/ /pubmed/22924097 Text en Copyright © Dental Research Center, Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Eshghi, AR.
Kowsari-Isfahan, R.
Rezaiefar, M.
Razavi, M.
Zeighami, S.
Effect of Iron Containing Supplements on Rats’ Dental Caries Progression
title Effect of Iron Containing Supplements on Rats’ Dental Caries Progression
title_full Effect of Iron Containing Supplements on Rats’ Dental Caries Progression
title_fullStr Effect of Iron Containing Supplements on Rats’ Dental Caries Progression
title_full_unstemmed Effect of Iron Containing Supplements on Rats’ Dental Caries Progression
title_short Effect of Iron Containing Supplements on Rats’ Dental Caries Progression
title_sort effect of iron containing supplements on rats’ dental caries progression
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422058/
https://www.ncbi.nlm.nih.gov/pubmed/22924097
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