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Identification of nonessential regions of the nsp2 protein of an attenuated vaccine strain (HuN4-F112) of highly pathogenic porcine reproductive and respiratory syndrome virus for replication in marc-145 cell

BACKGROUND: The regions in the middle of nonstructural protein 2 (nsp2) of porcine reproductive and respiratory syndrome virus (PRRSV) have been shown to be nonessential for PRRSV replication, and these nonessential regions are different in various viral strains. FINDING: In this study, the nonessen...

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Detalles Bibliográficos
Autores principales: Xu, Yan-Zhao, Zhou, Yan-Jun, Zhang, Shan-Rui, Tong, Wu, Li, Ling, Jiang, Yi-Feng, Tong, Guang-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422162/
https://www.ncbi.nlm.nih.gov/pubmed/22856599
http://dx.doi.org/10.1186/1743-422X-9-141